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TIPS ON CARING FOR YOUR SKIN

Caring for your skin while using Optune Pax® is important and can help you stay on treatment. In the clinical study, skin irritation was the most common side effect for people who used Optune Pax.

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To help prevent skin irritation under the arrays, follow these skin care recommendations*:

Caring for your skin

Good hygiene

Wash your hands before application and removal of arrays. Clean your skin with lukewarm water and mild, fragrance-free soap or body wash. Avoid alcohol-based soaps/body washes.

Clean, electric shaver

Remove hair from the abdomen using a clean, electric shaver. Do not use razor blades, as the blades may damage the skin and lead to skin irritation. You can repeat hair removal from the abdomen, as needed, when you replace the arrays. It can be a short trim and does not have to be a close shave. Call MyNovocure® at 1‑855‑281‑9301 if you need an electric shaver and we will provide you with one.

Skin barrier film

If you are using a skin barrier film, it must be removed and reapplied when replacing the transducer arrays.

Shift arrays

Shift array placement by ~2 cm (3/4 inch) at each array change to avoid placing them in the same spot. Move arrays back to the original position at subsequent changes.

Ventilation

Choose loose-fitting clothing when possible to allow air circulation around the arrays and to help minimize skin irritation or increasing array temperature.

Good contact

Use tape as needed. Change arrays two times per week (every 3-4 days) or when arrays loosen.

Monitor your skin and talk to your doctor

Check the skin under the arrays at every array change for signs of skin inflammation, redness, itchiness, blistering, and open wounds. Notify your doctor or nurse at the earliest signs of a skin issue.

If you do experience any redness or irritation:

Take a picture and contact your doctor right away.

Avoid placing the arrays in the affected area so you don’t cause further irritation.

Your doctor may be able to prescribe creams or other solutions to help manage your symptoms.

*Talk to your doctor for more information.

Proper array placement can help prevent skin irritation

Learn best practices

Indication and Important Safety Information

What is Optune Pax® approved to treat?

Optune Pax is an FDA-approved, wearable therapeutic device, used together with gemcitabine and nab-paclitaxel (a chemotherapy combination). It is indicated for the treatment of adult patients with locally advanced pancreatic cancer.

Who should not use Optune Pax?

Optune Pax for locally advanced pancreatic cancer is not for everyone. Talk to your doctor if you have:

  • An electrical implant. Use of Optune Pax together with electrical implants has not been tested and may cause the implanted device not to work properly
  • A known sensitivity to gels like the gel used on electrocardiogram (ECG) stickers or transcutaneous electrical nerve stimulation (TENS) electrodes. In this case, skin contact with the gel used with Optune Pax may commonly cause increased redness and itching. In rare cases, it may lead to severe allergic reactions that can cause a drop in blood pressure and difficulty breathing

Do not use Optune Pax if you are pregnant or are planning to become pregnant. If you are a woman who is able to get pregnant, you must use birth control when using the device. It is not known if Optune Pax is safe or effective during pregnancy.

What should I know before using Optune Pax?

Optune Pax should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune Pax.

  • Do not use any parts that did not come with the Optune Pax Treatment Kit sent to you by Novocure or given to you by your doctor
  • Do not get the device or transducer arrays wet
  • Please be aware that Optune Pax has a cord that plugs into an electrical socket. Be careful of tripping when it's connected
  • If you have an underlying skin condition where the transducer arrays are placed, discuss with your doctor whether this may prevent or temporarily interfere with Optune Pax treatment

What are the possible side effects of Optune Pax?

The most common side effects of Optune Pax used together with chemotherapy drugs were low neutrophils, low red blood cell count, low platelet count, low white blood cell count, diarrhea, nausea, vomiting, abdominal pain, constipation, fatigue, swelling, fever, pain, COVID-19, infection, respiratory tract infection, urinary tract infection, pneumonia, liver enzyme increased, weight loss, low potassium level, low albumin level, high blood sugar, muscle pain, neuropathy peripheral (damage to the nerves outside the brain and spinal cord), taste disorder, dizziness, difficulty sleeping, shortness of breath, hair loss, skin-related disorders, and low blood pressure.

Device-related skin adverse effects associated with the use of Optune Pax include skin inflammation, rash, itching, flat or raised spots, skin redness, skin irritation, skin reaction, and open sores. Other device-related adverse effects associated with the use of Optune Pax include overheating of the array, leading to pain and/or local skin burns, allergic reaction to the adhesive or gel from the transducer arrays, and local warmth and tingling sensation beneath the arrays. Talk to your doctor if you have any of these side effects or have any questions.

Please see the full Patient Information and Operation Manual (PIOM) for Optune Pax at OptunePax.com.

 

Indication and Important Safety Information

What is Optune Pax® approved to treat?

Optune Pax is an FDA-approved, wearable therapeutic device, used together with gemcitabine and nab-paclitaxel (a chemotherapy combination). It is indicated for the treatment of adult patients with locally advanced pancreatic cancer.

Who should not use Optune Pax?

Optune Pax for locally advanced pancreatic cancer is not for everyone. Talk to your doctor if you have:

  • An electrical implant. Use of Optune Pax together with electrical implants has not been tested and may cause the implanted device not to work properly
  • A known sensitivity to gels like the gel used on electrocardiogram (ECG) stickers or transcutaneous electrical nerve stimulation (TENS) electrodes. In this case, skin contact with the gel used with Optune Pax may commonly cause increased redness and itching. In rare cases, it may lead to severe allergic reactions that can cause a drop in blood pressure and difficulty breathing

Do not use Optune Pax if you are pregnant or are planning to become pregnant. If you are a woman who is able to get pregnant, you must use birth control when using the device. It is not known if Optune Pax is safe or effective during pregnancy.

What should I know before using Optune Pax?

Optune Pax should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune Pax.

  • Do not use any parts that did not come with the Optune Pax Treatment Kit sent to you by Novocure or given to you by your doctor
  • Do not get the device or transducer arrays wet
  • Please be aware that Optune Pax has a cord that plugs into an electrical socket. Be careful of tripping when it's connected
  • If you have an underlying skin condition where the transducer arrays are placed, discuss with your doctor whether this may prevent or temporarily interfere with Optune Pax treatment

What are the possible side effects of Optune Pax?

The most common side effects of Optune Pax used together with chemotherapy drugs were low neutrophils, low red blood cell count, low platelet count, low white blood cell count, diarrhea, nausea, vomiting, abdominal pain, constipation, fatigue, swelling, fever, pain, COVID-19, infection, respiratory tract infection, urinary tract infection, pneumonia, liver enzyme increased, weight loss, low potassium level, low albumin level, high blood sugar, muscle pain, neuropathy peripheral (damage to the nerves outside the brain and spinal cord), taste disorder, dizziness, difficulty sleeping, shortness of breath, hair loss, skin-related disorders, and low blood pressure.

Device-related skin adverse effects associated with the use of Optune Pax include skin inflammation, rash, itching, flat or raised spots, skin redness, skin irritation, skin reaction, and open sores. Other device-related adverse effects associated with the use of Optune Pax include overheating of the array, leading to pain and/or local skin burns, allergic reaction to the adhesive or gel from the transducer arrays, and local warmth and tingling sensation beneath the arrays. Talk to your doctor if you have any of these side effects or have any questions.

Please see the full Patient Information and Operation Manual (PIOM) for Optune Pax at OptunePax.com.

 

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US-OPP-00008 v1.0 April 2026