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ARRAY APPLICATION AND CHANGES

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Learning how to use your Optune Pax® arrays

Proper placement of Optune Pax arrays can be an important way to prevent skin irritation. When starting treatment, a trained medical professional or a Device Support Specialist (DSS) from Novocure® will teach you how to use the Optune Pax device, including how to place transducer arrays on the front and back of your abdomen according to the layout provided by your doctor, recharge and replace batteries, and plug in the device.

Applying and changing your arrays

Remember to change your arrays two times per week (every 3-4 days).

Step
0

Remove arrays gently with baby oil or lukewarm water and examine skin for signs of damage.

 

Be sure to disconnect the arrays from the device and leave the Optune Pax device outside the bathroom.

Step
1

Wash your skin with lukewarm water, a washcloth, and mild, fragrance-free, nonalcohol-based soap. You can take a full shower if you prefer.

Step
2

Remove hair from the abdomen using a clean, electric shaver. Do not use razor blades, as the blades may damage the skin and lead to skin irritation. You can repeat hair removal from the abdomen, as needed, when you replace the arrays. It can be a short trim and does not have to be a close shave.

Step
3

Apply topical skin products prescribed or recommended by your doctor (eg, moisturizing lotion, skin barrier film, corticosteroid, antibiotic cream; NOT alcohol- or petroleum-based products) and leave it on the skin for at least 20 minutes (or per the manufacturer’s instructions).

Step
4

Clean again. Remove excess residues before applying the arrays.

Step
5

Place new arrays. Shift the array placement slightly ~2 cm (3/4 inch) at each array change to avoid skin irritation. Move arrays back to the original position at subsequent changes. Avoid placing the arrays over surgical hardware (eg, screws or shunts), scars, or open wounds.

Step
6

Skincare management is an important part of your Optune Pax routine.

See tips for caring for your skin

Optune Pax is designed to fit into your everyday life

Find out how

Indication and Important Safety Information

What is Optune Pax® approved to treat?

Optune Pax is an FDA-approved, wearable therapeutic device, used together with gemcitabine and nab-paclitaxel (a chemotherapy combination). It is indicated for the treatment of adult patients with locally advanced pancreatic cancer.

Who should not use Optune Pax?

Optune Pax for locally advanced pancreatic cancer is not for everyone. Talk to your doctor if you have:

  • An electrical implant. Use of Optune Pax together with electrical implants has not been tested and may cause the implanted device not to work properly
  • A known sensitivity to gels like the gel used on electrocardiogram (ECG) stickers or transcutaneous electrical nerve stimulation (TENS) electrodes. In this case, skin contact with the gel used with Optune Pax may commonly cause increased redness and itching. In rare cases, it may lead to severe allergic reactions that can cause a drop in blood pressure and difficulty breathing

Do not use Optune Pax if you are pregnant or are planning to become pregnant. If you are a woman who is able to get pregnant, you must use birth control when using the device. It is not known if Optune Pax is safe or effective during pregnancy.

What should I know before using Optune Pax?

Optune Pax should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune Pax.

  • Do not use any parts that did not come with the Optune Pax Treatment Kit sent to you by Novocure or given to you by your doctor
  • Do not get the device or transducer arrays wet
  • Please be aware that Optune Pax has a cord that plugs into an electrical socket. Be careful of tripping when it's connected
  • If you have an underlying skin condition where the transducer arrays are placed, discuss with your doctor whether this may prevent or temporarily interfere with Optune Pax treatment

What are the possible side effects of Optune Pax?

The most common side effects of Optune Pax used together with chemotherapy drugs were low neutrophils, low red blood cell count, low platelet count, low white blood cell count, diarrhea, nausea, vomiting, abdominal pain, constipation, fatigue, swelling, fever, pain, COVID-19, infection, respiratory tract infection, urinary tract infection, pneumonia, liver enzyme increased, weight loss, low potassium level, low albumin level, high blood sugar, muscle pain, neuropathy peripheral (damage to the nerves outside the brain and spinal cord), taste disorder, dizziness, difficulty sleeping, shortness of breath, hair loss, skin-related disorders, and low blood pressure.

Device-related skin adverse effects associated with the use of Optune Pax include skin inflammation, rash, itching, flat or raised spots, skin redness, skin irritation, skin reaction, and open sores. Other device-related adverse effects associated with the use of Optune Pax include overheating of the array, leading to pain and/or local skin burns, allergic reaction to the adhesive or gel from the transducer arrays, and local warmth and tingling sensation beneath the arrays. Talk to your doctor if you have any of these side effects or have any questions.

Please see the full Patient Information and Operation Manual (PIOM) for Optune Pax at OptunePax.com.

 

Indication and Important Safety Information

What is Optune Pax® approved to treat?

Optune Pax is an FDA-approved, wearable therapeutic device, used together with gemcitabine and nab-paclitaxel (a chemotherapy combination). It is indicated for the treatment of adult patients with locally advanced pancreatic cancer.

Who should not use Optune Pax?

Optune Pax for locally advanced pancreatic cancer is not for everyone. Talk to your doctor if you have:

  • An electrical implant. Use of Optune Pax together with electrical implants has not been tested and may cause the implanted device not to work properly
  • A known sensitivity to gels like the gel used on electrocardiogram (ECG) stickers or transcutaneous electrical nerve stimulation (TENS) electrodes. In this case, skin contact with the gel used with Optune Pax may commonly cause increased redness and itching. In rare cases, it may lead to severe allergic reactions that can cause a drop in blood pressure and difficulty breathing

Do not use Optune Pax if you are pregnant or are planning to become pregnant. If you are a woman who is able to get pregnant, you must use birth control when using the device. It is not known if Optune Pax is safe or effective during pregnancy.

What should I know before using Optune Pax?

Optune Pax should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune Pax.

  • Do not use any parts that did not come with the Optune Pax Treatment Kit sent to you by Novocure or given to you by your doctor
  • Do not get the device or transducer arrays wet
  • Please be aware that Optune Pax has a cord that plugs into an electrical socket. Be careful of tripping when it's connected
  • If you have an underlying skin condition where the transducer arrays are placed, discuss with your doctor whether this may prevent or temporarily interfere with Optune Pax treatment

What are the possible side effects of Optune Pax?

The most common side effects of Optune Pax used together with chemotherapy drugs were low neutrophils, low red blood cell count, low platelet count, low white blood cell count, diarrhea, nausea, vomiting, abdominal pain, constipation, fatigue, swelling, fever, pain, COVID-19, infection, respiratory tract infection, urinary tract infection, pneumonia, liver enzyme increased, weight loss, low potassium level, low albumin level, high blood sugar, muscle pain, neuropathy peripheral (damage to the nerves outside the brain and spinal cord), taste disorder, dizziness, difficulty sleeping, shortness of breath, hair loss, skin-related disorders, and low blood pressure.

Device-related skin adverse effects associated with the use of Optune Pax include skin inflammation, rash, itching, flat or raised spots, skin redness, skin irritation, skin reaction, and open sores. Other device-related adverse effects associated with the use of Optune Pax include overheating of the array, leading to pain and/or local skin burns, allergic reaction to the adhesive or gel from the transducer arrays, and local warmth and tingling sensation beneath the arrays. Talk to your doctor if you have any of these side effects or have any questions.

Please see the full Patient Information and Operation Manual (PIOM) for Optune Pax at OptunePax.com.

 

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This website is intended only for US audiences seeking information on Optune Pax.

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US-OPP-00008 v1.0 April 2026